Monday, June 30, 2008

Rimonabant And The USA


The day of reckoning for 2007 has now come and gone for the FDA to review the medication rimonabant. Rimonabant is also known as Acomplia in Europe and other countries and Zimulti was then name it was to have in the United States. June 13th, the FDA voted against recommending this medication to hit the USA pharmacies. What does this mean for Sanofi-Aventis and what does the future of this medication look like for the United States?

Rimonabant has been past by many European countries for the treatment of obesity. It works differently than most other diet medications as well as has some possible benefits. Basically put, Rimonabant works by blocking receptors in the brain that are responsible for food cravings. When you’re eating less, it means generally you are consuming fewer calories and thus you lose weight. Some of the other potential benefits of this drug are that it has been shown to increase the “good” cholesterol while reducing “bad” cholesterol and has shown promise for helping smokers kick the habit.

While we don’t know all that went on in the FDA meeting, we do know that some of the issues that where brought up about this medication. One of the big obstacles they had issues with was its possible psychiatric side effects including suicidal influences. The FDA panel was not satisfied with the amount of feedback they had regarding this medication. And most likely they will keep an eye on it including watching the feedback coming in from other doctors around the world. It looks likely that a 50 month trail will then determine if this medication will be accepted into the USA market, a trail that would not be complete until 2010. The FDA had been scrutinized in the past for allowing drugs to hit the USA pharmacies in what some considered a too short of a study period. I suppose with such a possible popular medication such as Acomplia, that the FDA did not want to overlook all aspects of this medication before ever accepting it in the USA.

You can buy Rimonabant here

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Vahlouran's weblog

Side Effects of Some Drugs that Are Lowering Blood Pressure(part One)


Lowering blood pressure is a condition that is below the normal expected for an individual in a given environment. Blood pressure differs deeply with activity, age, medications, and underlying medical conditions

Some of the Drugs have some side effects that can cause lower blood pressure include blood pressure drugs, diuretics (water pills), heart medications (especially calcium antagonists-nifedipine/Procardia, beta blockers-propranolol/Inderal and others), depression medications (such as amitriptylene/Elavil), and alcohol.

Diuretics — diuretics are a big evil of lower blood pressure. It could cause lack of potassium in your body. Usually after taking diuretics, patient may suffer from weakness, leg cramps, or being tiredness however, it is not permanent. A patient can avoid these problems by taking some potassium tablets with diuretics. Diuretics such as amiloride (Midamar), spironolactone (Aldactone) or triamterene (Dyrenium) are called "potassium sparing" agents and provide equal of amount of potassium to your body. A lower blood pressure patient with diabetes can have some problems with diuretics. It may increase the blood sugar level. So, it is recommended to take permission from doctor before taking it.

Beta-blockers — patients of lower blood pressure feel insomnia, cold hands and feet, tiredness or depression, a slow heartbeat or symptoms of asthma after taking Beta-blockers. Patients of diabetes need to care while taking this medicine.

ACE inhibitors — a required amount of ACE inhibitors not effect badly to lower blood pressure patient but the drugs, such as captopril (Capoten), enalapril (Vasotec), lisinopril (Zestril or Prinivil), may cause a skin rash; loss of taste; a chronic dry, hacking cough; and in rare instances, kidney damage.

Angiotensin II receptor blockers — another evil for the patients of lower blood pressure. A patient may feel occasional faintness, so take care, and ask your doctor before taking the drug.

Calcium channel blockers —lower blood pressure patient may suffer from palpitations, swollen ankles, constipation, headache, or dizziness with this medicine. Form of Calcium channel blockers are Diltiazem (Cardizem), nicardipine (Cardene), Nifedipine (Procardia) and verapamil (Calan or Isoptin) which is injurious in lower blood pressure.

These side effects will continue in the next article "Side effects of some drugs that are Lowering Blood Pressure(part two)"

You can buy Procardia here

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Kaston's weblog

Well, Here's a List of the Common Allergy and Bronchial Asthma Drugs


Anyone who has read most of my articles on the subject of asthma would easily garner that I tend to favor the more natural and non-conventional approach in regards to dealing with the respiratory disorder.

However, I am aware that many people may not necessarily be ready or prepared to fore-go so-called asthma drugs for alternative asthma treatment options, most people might still want information on allergy and bronchial asthma drugs options.

This may be based on the fact that being as though some recent studies have shown that when you give allergy shots to children with allergies, not only do their allergy symptoms improve, they are also less likely to develop asthma and also, since many cases of asthma are triggered by allergies, it makes sense that if you control the allergies, you will have fewer asthma attacks, so for those who choose more of a conventional approach for asthma treatment, perhaps there may be a link between allergy and bronchial asthma drugs after all.

That said I'll list the common allergy and bronchial asthma drugs choices most people use:

1. Accolate

2. Singulair

3. Claratyne / Claratin

4. Telfast / Allegra

5. Telfast D / Allegra D

6. Telfast 120

7. Zyrtec

8. Becloforte / Beclovent

9. Qvar Inhaler

10. Pulmicort

11. Flixotide / Flovent

12. Ventolin

13. Volmax

14. Serevent Inhaler

15. Atrovent

16. Combivent

17. Advair Diskus

18. Rhinolast / Astelin

19. Nasonex

20. Tilade

Talk about an exhausting list of allergy and bronchial asthma drugs choices!

Well, now, that I've paid homage to the medical fraternity by presenting their options for controlling respiratory disorders, allow me to present some simple tips and alternatives to these common allergy and bronchial asthma drugs that you could use preferably exclusively, or in conjunction with the ones above

1. Avoid excessive temperature changes.

2. Ensure dust mites are reduced as much as possible in your home

3. Use a humidifier along with a heater in the cold seasons.

4. Keep fresh air circulating as much as possible in the home.

5. Keep the bed clean - put dust proof covers with zippers on the mattress and pillow. Wash bed sheets and blankets in hot water.

6. Do not let pets in the bedroom.

7. Do not smoke.

8. Maintain good ventilation / Light.

9. Close the windows when the air outside is full of exhaust from cars, pollution from factories.

10. Air out the house before the patient with asthma returns e.g. sweep, vacuum, paint, spray for insects, are of strong cleaners, cook strong smelling foods.

Also, do keep in mind that it is advised that you avoid Mucus-Forming foods such as Animal flesh and products, Most Grains, Junk and Processed Foods and even some so-called health-food products like Soy, Yeast, Bragg’s Liquid Aminos and Vinegar.

Replace these items with Fruits, Leafy and Root Vegetables and if desired less harmful whole grains like Brown rice, Quinoa, Amaranth and Millet occasionally.

Furthermore, proper food combination and the abstinence from drinking liquids of any kind with your meals is suggested as these will see to it that the diaphragm is not constricted by a clogged up digestive tract consequently making breathing much freer and smoother.

In addition, make the effort to avoid the use of microwaves, conventionally grown produce and polluted tap water for your optimal health.

So, there you have it, both sides and methods of controlling asthma.

Well…here's to freer breathing!

Aje

You can buy Advair Diskus here

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Nadya Cubillan's weblog

The Insider's Guide To Antihistamine Clarinex


Clarinex is a medication which can be taken year-round by those who suffer from allergies. It is also effective at treating those who suffer from hives or rashes. The active ingredient in this medication is desloratadine, which is an antihistamine. This blocks the immune system's production of the natural chemical histamine, which is produced when the body becomes sensitive to something.

Clarinex is effective at treating allergy symptoms produced from contact to both indoor allergens and outdoor ones. Anything from dust mites, pet dander, and mold spores, to pollen, grass or weeds can cause allergies.

Clarinex is widely used and popular because of its non-drowsy characteristic. Many antihistamines tell users to avoid machinery or driving while taking it, but Clarinex does not. This drug was also the first to boast that grapefruit juice did not affect its absorption.

It is also safe for most people who suffer form asthma to use this medication, although it is recommended that one contacts their doctor before mixing medications of any kind. Reported side effects include dry mouth, fatigue and a sore throat.

This medication comes in many forms which are taken according to age group, severity of symptoms, and other factors. The regular Clarinex tablets relieve symptoms for up to 24 hours and are safe for ages 12 and up. Clarinex 24-hour combines the power of antihistamine and decongestant for people with seasonal rhinitis and congestion. Children as young as 6 months of age can receive relief from indoor allergies, while children 2 and over can experience relief from outdoor ones, with the bubblegum flavored Clarinex syrup.

The syrup formula can also reduce the appearance of hives in children. Because many people are unable to easily take pills or tablets, Clarinex has provided a solution. For those who need another method, Clarinex Redi-tabs melt easily in the mouth. These also provide 24-hour relief and come in a fruit flavor.

The makers of Clarinex, Shering-Plough, claim that taking this medication in the morning will relieve symptoms all the way into the next morning when one awakes. This is a benefit, since many 24-hour solutions seem to wear off while one is sleeping.

Clarinex-D is a stronger formula which does require a prescription.

This also claims to have 24-hour relief all the way through to the next day. This member of the Clarinex family is for moderate to severe allergy sufferers.

You can buy Clarinex here

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darkcow's weblog

Sunday, June 29, 2008

Sweet Treatment From Ayurveda For Diabetes


Ayurvedic management of Diabetes depends on the strength of patient and type of diabetes he/she has. But some generalized management are mentioned below.

If the patient has sufficient strength panchakarma treatment can be started with snehana followed by vamana and virechana. Virechana can be repeated frequently. Dhanwantharam Gritham is apt for snehanam. Pizhichil is good for a week. Takradhara can also yield good results. Internal medicines that can be used are katakakhadiradi kashayam, aragvadhadi kashayam, nisadi kashayam, mehari dravakam. Apart from these ayaskriti and lodhrasavam are good.

Mehasamhari gulika, brihantmehantaka gulika, niruryadi gulika, svetagaunjadi gulika, haldi (turmeric), amalaki (gooseberry) choorna, nyagrodadhi churna, nisosiradi tailam,or eladi tailam can be added to the kashayams as the case may be. Shilajit, vasntakusumakara rasa, nag bhasma, vanga bhasma, and chandraprabha vati can be used favorably.

Hyponidd tablets, Diabecon tablets, Mehanil tablets, Glucova, Nishakatakadi qwath tablet can be used on regular basis.

Sugar in any form like rice, especially from fresh grains, potato, banana, and other such cereals and fruits are to be avoided. Fat intake should also be avoided. Tamarid and salt intake should be minimal. All bitter things are of help in general. Vegetables like bitter gourd, drumstick, patola(sponge gourd), okra (ladies finger) are good. So is neem (Azadirachta indica) and bilva (Aegle marmelos). It is also advised to decrease all food intakes by three quarters of normal. Wheat, barely and all millets are good. Some cases recover fully just with exclusively meat diet. Don't use polished grains as bryan is good for diabetes.

Shadangapaniyam or water boiled with ekanayakam (Salacia reticulate) is excellent to quench thirst in diabetics. Exercise within limits is advisable, yogic exercise, particularly matsyendra asanam is useful.

Sleep during daytime, sex, not resting after food intake and excessive labour is to be avoided.

You can buy Diabecon here

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MadandAngry's weblog

Five Best Exercise Ideas for Asthmatics


Do you want (or need!) to get more active, but you find yourself coughing, wheezing and so out of breath you have to stop and go back to your television program? You may have what doctors refer to as exercise-induced asthma. Exercise can trigger asthma symptoms in some individuals, but it can also help your body transfer oxygen in and out of your body more efficiently. Studies have shown that individuals who are overweight tend to have more trouble controlling their asthma than those who keep their weight to recommended levels. The key to exercising with asthma is to take a few precautions before you begin. Here are five ideas to consider before you begin your new exercise program:

1. First, consider the type of exercise that might work best for you. It is thought that exercise may trigger asthma attacks by exposing the lungs to cold, dry air. Our noses function to warm and humidify the air that we breathe in, but when we exercise, we tend to breathe through our mouths. Sports that involve prolonged constant activity or that take place in cold weather may cause more problems than other activities. Sports that may make your asthma worse include soccer, hockey, basketball, and long distance running. Sports that tend to be better for asthmatics include swimming, walking, football, and golfing because they involve shorter bursts of energy. Swimming in indoor pools can be particularly good because the air around the pool tends to be heated and humidified.

2. Talk to your doctor about using inhaled corticosteroids prior to exercise. A recent study by Dr. Hans Haverkamp published in the July 2007 issue of Journal of Allergy and Clinical Immunology found that using inhaled corticosteroids prior to exercise improved pulmonary gas exchange and performance and may increase arterial oxygenation.

3. Singulair (montelukast) has also recently been found to have a preventative effect for asthmatics when taken two hours before exercise and may last for up to 24 hours.

4. Use a short-acting albuterol inhaler (like Proventil or Ventolin) about ten minutes prior to exercising and carry the inhaler with you at all times. Remember, long-acting bronchodilators (like Serevent), inhaled corticosteroids and Singulair only help to prevent asthma attacks--they won't help you improve your breathing when you are having an acute asthma attack.

5. Drink plenty of water, especially on warm days. Warm up slowly and cool down slowly when exercising.

Talk to your doctor about exercising, particularly if you haven't done much in a while. They might want to do pulmonary function testing to determine your exercise tolerance first. Have fun!

You can buy Proventil here

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Lonagan's weblog

Friday, June 27, 2008

Exelon VP Thanks Speculators for Uranium Price Rise


We thought by now we’d heard it all. But the quote which follows, given to us in a tape-recorded telephone interview by the man who obtains nuclear fuel for the largest nuclear utility in the United States, surprised even us.

“From the point of view of today’s price, they did us a favor by sending a really strong signal to the production-side community that it was time to get out there and start looking to get stuff back into production,” Exelon Corp nuclear fuels vice president James Malone told StockInterview. Malone was referring to the uranium speculators and financial community, who have driven long-term uranium contracts to US$85/pound and the weekly spot price to $125/pound. “It may not have happened as quickly without this strong signal.”

And then we talked about the widening spread between the weekly spot and long-term uranium price.

“I think the sellers have the perception that prices should be higher in the spot market, but obviously the buyers aren’t sharing that perception right now,” Malone told us. Hence the pricing stalemate. “There isn’t any long-term activity to base a change in that price. It’s been flat for several weeks.”

Although the spot uranium price continues to set new records, many utilities are comfortable with the amount of U3O8 equivalent they have stockpiled. In his previous media interviews, Malone gave the impression that Exelon did not lack for the nuclear fuel to power the company’s 17 reactors, which produce about 20 percent of the U.S. nuclear electricity.

We asked if this were true. “That’s correct,” he responded. Others such as Entergy and FPL may not be as fortunate. The rumored scramble by at least three utilities for uranium equivalent could be one driver for the higher spot price.

And this brought us back to the uranium speculators. In late April, Malone wrote a guest commentary, which appeared in Fuel Cycle Week. In that issue Malone contended uranium speculators were driving up the spot price of uranium to make their investments in mining stocks more valuable.

We confirmed he continued to believe this. “I am not knocking the guys who are in it for financial gain. I can’t blame them for wanting to make money, but you have to understand what it is they are doing,” he said.

Malone cited the strong correlation between the stocks of junior mining companies and the uranium price. “The R squared is somewhere around 0.95,” he explained. R-square is a statistical coefficient of determination, which provides information about the validity of a model. This compares with TradeTech’s evaluation of the relationship to uranium stock share prices to the uranium price, which Gene Clark explained in an interview about a year ago.

Again he surprised us, having taken the time to meticulously study the ‘sell-side’ of the uranium market. But Malone admitted, “We didn’t look at all 450 of them.”

And why should he? Malone agreed with our premise that more than 90 percent of the ‘uranium’ companies are likely to disintegrate at some point. “Some of the smaller folks that are out there, really shouldn’t be there because they are not going to make it,” he said. “The other folks are going to fill the gap so that we’ll get a last marginal pound in at a reasonable price.”

When would we reach this ‘reasonable’ price? “It depends upon how some things like Cigar Lake come back to life because that’s such a large component of production,” Malone said. “Whether Shea Creek comes in during that timeframe – which will pretty much make a big dent – there’s several smaller ones. There’s a raft of properties people want to bring back into production. They may be able to only produce one or two million pounds a year.”

He agreed with our evaluation that many of those projections are falling short, especially on the smaller projects. But what about BHP Billiton's Olympic Dam? “I think Olympic Dam is so big that they can’t rush it,” he said. After we pointed out this could become the biggest open crater on earth, we both broke into laughter. “I think they’ve got to be reasonable in their approach to it,” he added.

We speculated about when hedge funds might begin selling uranium. Over the next few weeks, both Mestena Uranium LLC and an unnamed hedge fund plan to offer the largest amount of spot U3O8 and equivalent into the market in any single instance since last September. Dr. Robert Rich, a director of Yellowcake Mining, cautioned of a uranium ‘price adjustment’ at an unspecified time. “Bob and I used to share an office together when we were young and worked at Yankee Atomic,” Malone said.

He agrees there could be an adjustment. “It could be a two-phase thing. Some of the hedge funds may exit and just move on. Others may hang on and the market could stay above where it ought to be because it’s not yet fully rationalized with respect to the balance between supply and demand.” He added, “But, you could see some kind of adjustment that would bring it down a bit, and then take a longer time for it to reach a true rational equilibrium level.”

Malone’s conclusion? “The market fundamentals, if you simply look at the macro situation of supply and demand, it simply doesn’t support those kinds of numbers, especially in that time frame,” he said. “It is really a puzzle why some people have such a strong bullish position.”

And what does Malone believe is wrong with the time frame?

BOTTLENECK IN THE NUCLEAR RENAISSANCE?

Malone doesn’t think the nuclear renaissance is as imminent as many have forecast. “This is one of the things that frustrates me a little bit,” he started. “I think people need to understand: There’s an expectation of a tremendous number of plants around the world coming online real fast, and therefore driving demand up. Eventually, there will be that many plants. I just don’t think they can come on as fast as some people think they can.”

Where, then, is the obstacle? “You’ve got to get the forging to build the power plants,” Malone pointed out. “There are only a few places in the world that can do that right now.” He cited Japan Steelworks as the predominant supplier, and two others – one is South Korea and another in France. “There’s nobody in the U.S.,” he said.

“It’s a long haul to get all the pieces,” Malone explained. “Japan Steelworks is putting out a slightly greater than 100 percent increase in their capacity to produce the forgings. The process is going to take several years, probably on the order of five to ten to get the real production up to where we want it to be.”

Since 1974, Japan Steelworks (JSW) has manufactured the forgings of components found in nuclear plants. The company has manufactured about 130 reactor vessels now used around the world – nearly 30 percent.

The company recently announced it would increase investments in manufacturing capacity to meet the global demand. One of the company’s main targets is to supply new nuclear pressure vessels to the U.S. and Chinese markets. JSW anticipates orders for 25 pressure vessels and 31 from the U.S. Some wonder about the challenges increased activity in the nuclear sector holds for the supply chain’s growing demand for heavy forgings and other major components.

According to the Nuclear Energy Institute (NEI), license applications for more than 18 new reactors could be filed by a dozen energy companies by 2009.

On Wednesday, Richmond, Virginia-based Dominion Resources reportedly asked Hitachi and General Electric to build its third nuclear-powered electric generating unit at the company’s North Anna power station in Mineral, Virginia. Earlier this month, Dominion awarded GE Energy’s nuclear business a contract to secure critical, ‘long-lead’ components for the nuclear power unit. This order included large forgings required for GE’s ESBWR reactor design. The forgings would likely come from Japan Steelworks.

A long lead time is required for the forgings. “It’s a long haul to get all the pieces,” Malone told us. “Right now, the facilities even for assembling a reactor in the United States are limited in their capabilities.”

A bottleneck could result in obtaining heavy forgings as well as assembling them. In August 2006, Constellation Energy announced it had entered into an agreement with AREVA to procure 44 heavy forgings – needed for the reactor pressure vessel and steam generators – to construct the first potential nuclear power plant of a planned U.S. EPR fleet. The forgings will reportedly be manufactured into the final components at the BWX Technologies facility in Mount Vernon, Indiana or AREVA’s facility in Chalon-St. Marcel.

Construction on the Dominion plant could start as early as 2010. It could go into production by 2014. This matches the timetable Malone cautioned us about. He pointed to progress made by NRG Energy made at the company’s South Texas project.

On April 27th, NRG announced an agreement with Tokyo Electric Power Company (TEPCO) to help develop the combined construction and operating license for NRG Energy’s application to the U.S. Nuclear Regulatory Commission later in 2007. “The good news is that the ABWR (Advanced Boiling Water Reactor) has been built in Japan and is under construction in Taiwan,” Malone said. The NRC has already certified General Electric’s ABWR design. “It’s a known entity and licensed in the United States,” Malone explained.

Doesn’t this appear like enormous momentum moving forward? “I think it’s going to be a slow build up,” he told us. “It’s like one of those curves that’s kind of slow, then has the knee out there – the hockey stick – and then it starts to go up.” But he also warned, “We have to have the folks to operate them. We have to have the infrastructure to build them. We have to have the regulatory oversight. If we go at it the right way as an industry, I think it can be terribly successful.” He believes the renaissance will emerge several years down the road. “Probably on the order of five to ten years to get the real production to where we want it to be,” Malone said.

Malone firmly believes there will be a nuclear renaissance in the United States. “We need electricity, there’s a tremendous amount of emotion with respect to greenhouse gases, and nuclear can be base load electricity without the greenhouse gases,” he told us. “A lot of people are realizing that now, especially when James Lovelock takes the position that nuclear power is a good thing to do for electricity production. I think he’s got the right message.”

Our final surprise was that Malone had a copy of Investing in the Great Uranium Bull Market. “I was impressed by the fact that he (James Lovelock) was right in the foreword.” Dr. Lovelock actually wrote the foreword for this publication and personally endorsed our book, writing, “'I unhesitatingly recommend it to politicians, environmentalists and all those concerned about our future.”

And finally we asked whether or not Exelon Corp would participate in NYMEX futures trading. “That’s too early to say,” Malone responded. “My position on that is we need to digest what we were told, learn how it works, observe it – and if we believe there’s some advantage or some useful purpose for us participating, then we would consider it.”

And finally we asked whether or not Exelon Corp would participate in NYMEX futures trading. “That’s too early to say,” Malone responded. “My position on that is we need to digest what we were told, learn how it works, observe it – and if we believe there’s some advantage or some useful purpose for us participating, then we would consider it.”

But what about the safety of nuclear reactors, especially from terrorist attacks? After September 11th the U.S. Nuclear Regulatory Commission mandated new security measures at U.S. nuclear power plants. These measures included altered or new physical barriers, increased security personnel, training enhancements and additional surveillance equipment. According to Exelon Corp’s website, the total cost of these enhancements exceeded $150 million in capital spending and now includes approximately $20 million in additional annual operating expenses each year.

How do these enhancements hold up?

In a recent note from the Nuclear Energy Institute, legendary actor Paul Newman (and now also becoming a legend for his line of food products) toured Entergy’s Indian Point nuclear plant outside New York City this past Monday (by the way, Paul Newman also has our book, Investing in the Great Uranium Bull Market). Mr. Newman reported as follows:

“I recently toured the Indian Point nuclear plant and I expected to be shown safety and security at the plant. But what I saw exceeded my expectations. No Army or Navy base I’ve ever visited has been more armored and I couldn’t walk 30 feet inside the plant without swiping my key card to go through another security check point. There was security at every turn, and the commitment to safety is clear.”

We agree with both Mr. Malone and Mr. Newman that nuclear power will be more important for the anticipated dramatic electricity growth in the future. And no one really knows precisely how much longer the spot uranium price could continue higher, where it will peak and at which price level would be sustainable. But everyone likes to guess about these matters.

COPYRIGHT© 2007 by StockInterview, Inc. ALL RIGHTS RESERVED.

You can buy Exelon here

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Drathuu's weblog

An Inside Look at Prostate Cancer Cures In The Various Forms Of ...


Prostate cancer cures lay in the various forms of treatments available as therapy for the disease.

Common Treatments for Prostate Cancer

Radiation, hormone therapy, radical prostatecomy, chemotherapy, and cryotherapy, which seeks to destroy cancer cells by freezing them, are amongst the most common treatments for prostate cancer, and the closet modern medicine has come to finding prostate cancer cures.

Radiation for prostate cancer treatment involves the use of external-beam radiation therapy, and radioactive seed implants.

Prostate cancer hormone therapy implements the use of drugs to stop the biological production of male sex hormones. Androgens are male sex hormones that have been clinical linked to the development of prostate cancer when produced in excess.

Radical prostatecomy is the surgical removal of the prostate gland. There are two radical prostatecomy surgical procedures available, retropubic surgery, and perineal surgery. The retropubic surgery removes the prostate gland through an incision placed below the navel. The perineal surgery features an incision for removal placed between the anus and scrotum.

Conventional Prostate Cancer Medications

Luteinizing hormone-releasing analogs (LHRH) are designed to lower testosterone levels. Such prostate cancer medications are administered via injections and can be given monthly or every three, six, or nine months. Many metastases (with the cancer spreading outside of the prostate gland) prostate cancer patients opt for this round of prostate cancer treatments as opposed to a surgical removal of their testicles.

Plenaxis is the newest LHRH antagonists. The drug works to lower testosterone but does not cause a sharp rise in testosterone levels before taking affect, as LHRH analogs do. LHRH antagonists can only be used in men who are not able to use other forms of hormonal treatment. Abarelix, Lupron, Zoladex, Eulexin, and Casodex are other common types of LHRH antagonists.

Finding Prostate Cancer Cures Through Clinical Trials

Clinical trials serves as one way of finding prostate cancer cures. All prostate cancer medications must take pass the three phases required to gain approval from the Food and Drug Administration.

Phase I of the clinical trials test the safety of a new drug. The second clinical phase is designed to determine how the proposed new prostate cancer treatment works. Patients are given the drug in high doses during this phase. The patients are watched to see what effect the test drug has on their prostate cancer. The final phase of clinical trial testing pits test medications against standard treatments. A control group is given dosages of the test drug while a second group uses standard methods of medicine-with the effects documented.

You can buy Eulexin here

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Gnarl's weblog

Thursday, June 26, 2008

Pros And Cons Of Popular Impotence Treatments


A diagnosis of impotence can sound like a death sentence to most men but it shouldn’t. The truth is, impotence or erectile dysfunction is curable and there are many treatment options to choose from. These include medications, mechanical devices, and surgery.

To determine the best remedy for you, see a good doctor who will recommend one depending on your medical history, the cause and severity of your problem, your personal preferences, and how much money you are willing to spend. Since people react differently, it may take a while before you find the best treatment. Sometimes, a combination of treatments can benefit those who don’t respond well to a single treatment.

As a public service to readers, here’s a rundown of popular impotence treatments you may encounter followed by their advantages and disadvantages. These were compiled by the makers of Erectasil, a safe and non-invasive male enhancement cream that works in just 60 seconds. For more information, visit http://erectasil.com.

Oral medications – Viagra (sildenafil) was the first impotence pill to be approved by the US Food and Drug Administration (FDA). This was later followed by Levitra (vardenafil) and Cialis (tadalafil). Known as phosphodiesterase (PDE) inhibitors, these drugs are usually taken an hour before sex and enhance the effects of nitric oxide, a chemical that relaxes smooth muscles in the penis and allows increased blood flow for erections to occur.

Unlike injections that cause instant erections, these drugs produce an erection only after physical and psychological stimulation. While these drugs are similar, they vary in dosage, duration of effectiveness, and side effects. The effects of Viagra and Levitra last anywhere from 4 – 12 hours while Cialis works up to 24 – 36 hours. None should be used more than once a day.

“Although these medications can help many people, not all men can or should take them to treat erectile dysfunction. If you've had a heart attack, stroke or life-threatening heart rhythm during the last six months, don't take these medications. If you've been told that sexual activity could trigger a cardiac event, discuss other options with your doctor. In addition, don't take Viagra, Levitra or Cialis with nitrate medications, such as the heart drugs nitroglycerin (Nitro-Bid, others), isosorbide mononitrate (Imdur) and isosorbide dinitrate (Isordil). The combination of these medications, which work to widen (dilate) blood vessels, can cause dizziness, low blood pressure, and circulation and heart problems,” warned the MayoClinic.Com.

Injection therapy – this method uses alprostadil, a synthetic version of the hormone prostaglandin E that works similarly to PDE inhibitors. It is injected into the side or base of the penis using a fine needle that produces very little pain. Erection occurs in five to 20 minutes and lasts for an hour. The downside? This treatment can be expensive and may produce adverse side effects like bleeding and priapism (long and painful erections). To cut costs, alprostadil can be mixed with other drugs like papaverine hydrochloride and phentolamine.

Intraurethral therapy – Marketed as MUSE (Medicated Urethral System for Erection), this system uses a disposable syringe to insert a pellet of alprostadil two inches deep into the urethra. The pellet is about half the size of a grain of rice. Once absorbed by tissues in the penis, the drug increases blood flow, producing an erection in 8 to 10 minutes that lasts for 30 minutes to an hour. The bad news: although needles aren’t involved, the procedure can be painful and uncomfortable.

“The most common side effects are aching in the penis, testicles, and area between the penis and rectum; warmth or burning sensation in the urethra; redness from increased blood flow to the penis; and minor urethral bleeding or spotting, according to the National Kidney and Urologic Diseases Information Clearinghouse.

Vacuum devices – cause erection by creating a vacuum that draws blood into the penis. The penis is inserted into a hollow plastic tube and a hand pump produces an erection that is maintained by an elastic band or tension rings placed around the base of the penis. The band is removed after intercourse. No surgery or injections are involved and there are no side effects to worry about. Moreover, this device can be used anytime. Still, it may not be for everyone.

“Using a vacuum device involves a mechanical process. They generally take from 5 to 10 minutes to set up, so they can interfere with foreplay. The body shapes of some men can make it difficult to apply these devices. Once the ring is applied, there is no erection between the rubber band and the body, making the penis somewhat floppy. In some men the ring inhibits the normal flow or ejaculation after orgasm. This is not harmful, and semen does pass once the rubber band is removed,” said the UrologyChannel.Com.

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therealmonkey's weblog

Epileptic Seizure Solution


Being a very unpredictable disease, epilepsy frequently rules the lives of those attacked by it. The solitary way to maintain control over symptoms is by using assorted combinations of anti-convulsive drugs and developing a well-balanced style of living that keeps excesses of all kinds away.

Mysoline, is an anti-convulsive drug that stops seizures triggered by epilepsy. This form of long-term treatment can be taken for an indefinite period of time. However long you keep taking it, be absolutely sure a close contact with your doctor is maintained for a professional monitoring of your condition.

Treatment Specifics

This medication should be administered as suspension or capsules, and quantity depends on the intensity of the problem, body weight and age. If you choose Mysoline in liquid form, keep it in a dark location and vigorously shake the bottle prior to every usage to ascertain you get the accurate amount.

If you miss a dose, take it as soon as possible. If it is within 1 hour of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Warnings

The only health circumstance that is totally mismated is porphyria, an inherited metabolic disorder.

At the conclusion of treatment, never discontinue taking this medication abruptly, as this may contribute to stronger seizures than you've experienced previously. Withdrawal must be a gradual process.

Taking into consideration the fact that this drug is, for the most part, administered for an eminently

long period of time, intermittent blood tests are imperative to maintain an accurate view of your health condition, and to inhibit any possible system decline in quality.

Beware of drug interactions

Prior to beginning any new drug therapy, make sure it doesn't interject with this medication.Or you risk to jeopardise the effectiveness of either. Medications that are susceptible to Mysoline incumbrance include: estrogen based oral contraceptives, certain antibiotics, blood-thinning drugs, anti-depressants and steroidal drugs

On that account, try to abstain from all alcoholic drinks while using this medication. In order to circumvent possible unwanted side effects, it is important to inform your health care provider on the use of this drug.

There are an abundance of other drugs that can be safely mixed with Mysoline without triggering any negative effects. Your doctor is the most qualified person to talk to when needing to interpret other assorted health troubles that inevitably appear.

Use this medication exactly as prescribed. Do not change from one manufacturer's product to another without consulting your doctor.

Continue taking Mysoline even if you feel well. Do not miss any doses.

Mysoline gives you the effectiveness of phenobarbital plus additional protection. A patient whose seizures have not been controlled by phenobarbital may have better results from Mysoline.

study in children-which also included Depakote (valproate)-focused on the rate of side effects. Only 8% of the children who were given Mysoline had to stop taking it because of side effects. Phenobarbital, which can be an excellent medication, often is avoided in children because of the possibility of mental slowing. By using Mysoline alone, children can enjoy many of the same benefits while avoiding this problem because the amount of phenobarbital produced by breaking down the Mysoline is low.

It is important to remember that no single combination of antiepileptic medications is perfect for everyone. Sometimes, a series of combinations must be tried before finding what is best for the individual patient.

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Birus Durden's weblog

MaxoDerm Cream - For Unmatched, Ultimate Male Enhancement


If you are among the thousands of people around the world that are prone to weak erections or a have a undersized penis then MaxoDerm cream is the total on in one solution for you.

The key to your success

As with any medication or supplement the key is the delivery or application method. Being a cream form MaxoDerm is applied at the point where it is require - directly onto the penis. This leads to a fast acting, stronger erections that last longer, keeping both you and your partner satisfied.

Regular user of MaxoDerm cream obviously increases you size and firmness but also has the added benefit of boosting your sexual stamina, which many users also reporting increased intensity of orgasms too.

What Will You Experience?

When applied MaxoDerm will invoke a warm sensation through your penis, this is normal and actually feels good. This sensation is the first stage of the application and proof that the cream is starting to work it's magic.

The Technical Stuff That Erections Are Made Of

To form an erection is a complicated process but starts with sexual arousal. This sexual stimulation releases nitric oxide in the corpus cavernous. This in turn diffuses into the muscle cells lining the arteries of your copus cavernous, causing them too relax. This relaxation then allows the arteries to

The mechanism of action involves a complicated, complex interaction of physiological processes - sexual arousal results in a release of nitric oxide in the corpus cavernous which diffuses into smooth muscle cells lining the arteries of the corpus cavernous thereby relaxing them. It is this relaxation that allows arteries to become flooded with blood and produce an erection.

MaxoDerm cream is usually applied liberally. It should be directly applied onto the penis and massaged lightly for approximately 5-10 minutes. It is recommended that you MaxoDerm for across a twelve week period to gain maximum effect, although it can be just as effective as a one off application.

Quick Acting Cream

Instead of being processed through the body's digestive system and being diluted and destroyed in processes as usually occurs when swallowing a pill, tablet, or capsule, MaxoDerm cream has a patent pending formula - by the name of vasotran auctum - which causes an immediate impact because its ingredients directly stimulate the skin tissue associated with the arousal and orgasm. The main contents of vasoatran auctum ingredints include:

- zinc oxide

- muira pauma

- catauba extract

- methyl nicotinatewhite nettle extract

- L-Arginine

- saw palmetto extract

MaxoDerm cream enhances the results directly upon intended site of action, limiting exposure of the rest of the body to the ingredients.

MaxoDerm cream is unlike any other male enhancement products due to its unique formula that contains clinically tested ingredients perfect dosage for the best guaranteed results.

Research and Customer Feedback

A test of the cream was carried out in accordance with Barmensen Labs' Internal Compliance Initiatives. This test surveyed 150 users. The results are summarised below and I'm sure you'll agree they seem to back up the claim that MaxoDerm is the premier erection enhancement cream on the market.

- 78 % experienced a significant enhancing of their erecting firmness

- 83 % felt that the product began working in less than 60 seconds

- 71 % have noticed a great improvement in sensation

Special Note: It is important to know that you do not need prescription for this male enhancement and it has been evaluated and approved by the Food and Drug Administration.

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SirCruizer's weblog

Diflucan For Thrush – Does Diflucan Cure Yeast Infection?


Diflucan also known as Fluconazole is a medical treatment for thrush, known in medical terms as “vaginal candidiasis” or in casually as “yeast infection”. Yeast infections can range from very annoying right through to so painful some women are not able to walk without extreme pain.

The medical treatment of yeast infection centre around medications that slow the growth of the yeast “Candida Albicans”, the cause of thrush. Candida is part of the natural flora of the human body, growing on the skin but favouring the warm moist areas such as the vagina or under folds of skin. Candida can also grow in the mouth and the gastrointestinal tract.

If the body has been under stress, such as recent use of antibiotics or a change in diet, the acidity of the skin can change creating an environment that favour the growth of Candida. It is these times of Candida overgrowth that people can develop the common symptoms – itch, burning sensation, cheesy discharge and even pain and swelling.

During these episodes treatment with antifungal agents such as Diflucan can help reduce the load of fungi, thus reducing the symptoms. Fluconazole can be given in a variety of ways. One of the main methods is the placement of a medicated “pessary” – a tablet designed to be placed inside the vagina, where the Diflucan can act locally. In more acute infections table form that is swallowed may be offered. When it is taken this way it usually needs to be taken for about seven days.

It is important to note that with the medical treatments of thrush is that whilst removing the yeast will stop the symptoms, if the body still has the same acidic imbalance then the thrush will be able to grow again. This is the common complaint of modern medical treatments when compared with natural treatments.

As with all medical conditions it is recommended you see you local practioner before you start any new treatment. Many doctors are now highly sympathetic to people wishing to treat with natural remedies. Remember is does not always have to be Diflucan to treat thrush infection in the first meeting.

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Telantaa's weblog

Wednesday, June 25, 2008

Retinoblastoma is a Cancer of Retina - You Know About This Eye Cancer?


Retinoblastoma is a cancer of the retina. Retinoblastoma is the most common primary ocular malignancy of childhood. Although this disorder can occur at any age, it usually develops in young children. Most cases of retinoblastoma occur in only one eye, but both eyes can be affected. Untreated, retinoblastoma is almost always fatal, hence the importance of early diagnosis and treatment.

Retinoblastoma can occur in two forms:

An inherited form where there are often tumors in both eyes (bilateral) or sometimes only in one eye.

A non-inherited form where there is a tumor in only one eye (unilateral)

Retinoblastoma is related to chromosome 13. Retinoblastoma occurs when a cell of the growing retina develops a mutation in the RB gene (a tumor-suppressor gene). This mutation causes the cell to grow out of control and become cancerous.

Mutations in the RB1 gene are inherited in an autosomal dominant pattern, which means that one copy of the altered gene in each cell is sufficient to increase cancer risk. A person with retinoblastoma may inherit an altered copy of the gene from one parent, or the altered gene may be the result of a new mutation.

The most common way of presentation is a white reflex (leukocoria) behind the pupil. This is sometimes called the cat's eye reflex. A white glow in the eye that is often seen in photographs taken with a flash; instead of the typical "red eye" from the flash, the pupil may appear white or distorted. White spots in the pupil, crossed eyes, A red, painful eye poor vision, the iris may be a different color in each eye.

A few special tests like ultrasonography, CT scan, X-rays, MRI, blood tests, spinal tap, bone marrow biopsy etc. may be done to establish the diagnosis and to find out the extent of the disease.

Treatment options depend upon the size and location of the tumor. Small tumors may be treated by laser surgery. Radiation and chemotherapy may be needed if the tumor has spread beyond the eye. Chemotherapy is the treatment of choice for most unilateral cases.

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Telantaa's weblog